accord
https://iademos.com/Catalogo/
opcache.revalidate_freq = 10
realpath_cache_size = 64k
realpath_cache_ttl = 120

n php-fpm config (usually /etc/php5/fpm/php-fpm.conf)
*** https://serverfault.com/questions/189940/how-do-you-restart-php-fpm
https://myjeeva.com/php-fpm-configuration-101.html

https://haydenjames.io/php-fpm-tuning-using-pm-static-max-performance/
pm = dynamic – the number of child processes is set dynamically based on the following directives: pm.max_children, pm.start_servers,pm.min_spare_servers, pm.max_spare_servers.

pm = ondemand – the processes spawn on demand (when requested, as opposed to dynamic, where pm.start_servers are started when the service is started.

pm = static – the number of child processes is fixed by pm.max_children.
pm = ondemand
pm.max_children = 50
pm.process_idle_timeout = 10s
pm.max_requests = 500

Set MySQL Query Cache Size no larger than 100 to 200MB!
query_cache_type = 2
query_cache_limit = 256K
query_cache_min_res_unit = 2k
query_cache_size = 80M

-- mariadb --
thread_pool_min_threads

hread_pool_min_threads 

thread_pool_size                        | 12                        |
| thread_pool_stall_limit                 | 500                       |
| thread_stack                            | 294912   

query_cache_size             | 0
--
Include '/etc/httpd/conf/plesk.conf.d/server.conf'
IncludeOptional '/etc/httpd/conf/plesk.conf.d/webmails/*.conf'
IncludeOptional '/etc/httpd/conf/plesk.conf.d/vhosts/*.conf'
IncludeOptional '/etc/httpd/conf/plesk.conf.d/forwarding/*.conf'
IncludeOptional '/etc/httpd/conf/plesk.conf.d/wildcards/*.conf'

Alias "/plesk-stat" "/var/www/vhosts/system/iademos.com/statistics"
                Alias /webstat /var/www/vhosts/system/iademos.com/statistics/webstat
                Alias /webstat-ssl /var/www/vhosts/system/iademos.com/statistics/webstat-ssl
/var/www/vhosts/system/iademos.com/statistics

        access_log "/var/www/vhosts/system/iademos.com/logs/proxy_access_ssl_log";
        error_log "/var/www/vhosts/system/iademos.com/logs/proxy_error_log";